I travel frequently and have found that my cats are more comfortable when they have someone in the house to take care of them, rather than a visiting caretaker. My house is a block from the tidepools with lots of paths to walk above the beach, near a small harbor with scenery and places to eat, and in a quiet neighborhood. If you'd like to visit San Francisco and take in the culture, it's a 30 minuter drive away.
My guest bedroom and bath are very comfortable. It's up the stairs so you should be able to negotiate them. House is roomy and furnished nicely, cottage style, large yard and decks.